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Schweizer's reagent is the metal ammine complex with the formula [Cu(NH3)4(H2O)2](OH)2. This deep-blue compound is used in purifying cellulose.
It is prepared by dissolving copper(II) hydroxide in a solution of ammonia.
It forms an azure solution. Evaporation of these solutions leaves light blue residue of copper hydroxide, reflecting the lability of the copper-ammonia bonding. If conducted under a stream of ammonia, then deep blue needle-like crystals of the tetrammine form. In presence of oxygen, concentrated solutions give rise to nitrites Cu(NO2)2(NH3)n. The nitrite results from oxidation of the ammonia.